Szczegóły publikacji
Opis bibliograficzny
Structural evolution of supported lipid bilayers intercalated with quantum dots / Magdalena Włodek, Anna Slastanova, Laura J. Fox, Nicholas Taylor, Oier Bikondoa, Michał SZUWARZYŃSKI, Marta Kolasińska-Sojka, Piotr Warszyński, Wuge H. Briscoe // Journal of Colloid and Interface Science ; ISSN 0021-9797. — 2020 — vol. 562, s. 409-417. — Bibliogr. s. 416-417, Abstr. — Publikacja dostępna online od: 2020-11-26
Autorzy (9)
- Włodek Magdalena
- Slastanova Anna
- Fox Laura J.
- Taylor Nicholas
- Bikondoa Oier
- AGHSzuwarzyński Michał
- Kolasińska-Sojka Marta
- Warszyński Piotr
- Briscoe Wuge H.
Słowa kluczowe
Dane bibliometryczne
| ID BaDAP | 129248 |
|---|---|
| Data dodania do BaDAP | 2020-07-14 |
| Tekst źródłowy | URL |
| DOI | 10.1016/j.jcis.2019.11.102 |
| Rok publikacji | 2020 |
| Typ publikacji | artykuł w czasopiśmie |
| Otwarty dostęp |  |
| Czasopismo/seria | Journal of Colloid and Interface Science |
Abstract
Hypothesis Supported lipid bilayers (SLBs) embedded with hydrophobic quantum dots (QDs) undergo temporal structural rearrangement. Experiments Synchrotron X-ray reflectivity (XRR) was applied to monitor the temporal structural changes over a period of 24 h of mixed SLBs of 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine (POPC) / 1-palmitoyl-2-oleoyl-sn-glycero-3-phospho-ethanolamine (POPE) intercalated with 4.9 nm hydrophobic cadmium sulphide quantum dots (CdS QDs). The QD-embedded SLBs (QD-SLBs) were formed via rupture of the mixed liposomes on a positively charged polyethylene imine (PEI) monolayer. Atomic force microscopy (AFM) imaging provided complementary characterization of the bilayer morphology. Findings Our results show time-dependent perturbations in the SLB structure due to the interaction upon QD incorporation. Compared to the SLB without QDs, at 3 h incubation time, there was a measurable decrease in the bilayer thickness and a concurrent increase in the scattering length density (SLD) of the QD-SLB. The QD-SLB then became progressively thicker with increasing incubation time, which – along with the fitted SLD profile – was attributed to the structural rearrangement due to the QDs being expelled from the inner leaflet to the outer leaflet of the bilayer. Our results give unprecedented mechanistic insights into the structural evolution of QD-SLBs on a polymer cushion, important to their potential biomedical and biosensing applications.