Szczegóły publikacji

Opis bibliograficzny

Acoustic radiation force optical coherence elastography for evaluating mechanical properties of soft condensed matters and its biological applications / Hsiao-Chuan Liu, Piotr KIJANKA, Matthew W. Urban // Journal of Biophotonics ; ISSN 1864-063X. — 2020 — vol. 13 iss. 3 art no. e201960134, s. 1–12. — Bibliogr. s. 11–12, Abstr. — Publikacja dostępna online od: 2019-12-23. — P. Kijanka - pierwsza afiliacja: Mayo Clinic, Rochester, Minnesota, USA

Autorzy (3)

Słowa kluczowe

acoustic radiation forceoptical coherence tomographysoft condensed matterultrasoundoptical coherence elastographymicellar fluid

Dane bibliometryczne

ID BaDAP128407
Data dodania do BaDAP2020-04-22
Tekst źródłowyURL
DOI10.1002/jbio.201960134
Rok publikacji2020
Typ publikacjiartykuł w czasopiśmie
Otwarty dostęptak
Czasopismo/seriaJournal of Biophotonics

Abstract

Evaluating mechanical properties of biological soft tissues and viscous mucus is challenging because of complicated dynamic behaviors. Soft condensed matter models have been successfully used to explain a number of dynamical behaviors. Here, we reported that optical coherence elastography (OCE) is capable of quantifying mechanical properties of soft condensed matters, micellar fluids. A 7.5 MHz focused transducer was utilized to generate acoustic radiation force exerted on the surface of soft condensed matters in order to produce Rayleigh waves. The waves were recorded by optical coherence tomography (OCT). The Kelvin-Voigt model was adopted to evaluate shear modulus and loss modulus of soft condensed matters. The results reported that various concentrations of micellar fluids can provide reasonable ranges of elasticity from 65.71 to 428.78 Pa and viscosity from 0.035 to 0.283 Pa center dot s, which are close to ranges for actual biological samples, like mucus. OCE might be a promising tool to differentiate pathologic mucus samples from healthy cases as advanced applications in the future.

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