Szczegóły publikacji
Opis bibliograficzny
Novel whey protein isolate-based highly porous scaffolds modified with therapeutic ion-releasing bioactive glasses / Michał DZIADEK, Timothy E. L. Douglas, Kinga Dziadek, Barbara ZAGRAJCZUK, Andrada Serafim, Izabela-Cristina Stancu, Katarzyna CHOLEWA-KOWALSKA // Materials Letters ; ISSN 0167-577X. — 2020 — vol. 261 art. no. 127115, s. 1–5. — Bibliogr. s. 4–5, Abstr. — Publikacja dostępna online od: 2019-12-03. — M. Dziadek - dod. afiliacja: Faculty of Chemistry, Jagiellonian University, Krakow; Engineering Dept., Lancaster University, United Kingdom
Autorzy (7)
- AGHDziadek Michał
- Douglas Timothy E. L.
- Dziadek Kinga
- AGHZagrajczuk Barbara
- Serafim Andrada
- Stancu Izabela-Cristina
- AGHCholewa-Kowalska Katarzyna
Słowa kluczowe
Dane bibliometryczne
| ID BaDAP | 126641 |
|---|---|
| Data dodania do BaDAP | 2020-01-13 |
| Tekst źródłowy | URL |
| DOI | 10.1016/j.matlet.2019.127115 |
| Rok publikacji | 2020 |
| Typ publikacji | artykuł w czasopiśmie |
| Otwarty dostęp |  |
| Czasopismo/seria | Materials Letters |
Abstract
In this work, for the first time, a material derived from food industry waste – whey protein isolate – and a material commonly used in bone regeneration – bioactive glasses – were combined to obtain novel composite biomaterials with potential applications in bone tissue engineering (BTE). Additionally, to obtain pro-angiogenic properties, sol–gel-derived BGs doped with Cu2+ and Co2+ ions were used. Using a simple gas foaming method, ready-to-use (sterile), bioactive scaffolds with high porosity (above 70%), fully connected pore networks, and pore size suitable for BTE applications (80–350 μm) were obtained. Furthermore, scaffolds showed additional functionalities – calcium phosphate-forming ability and gradual release of therapeutic ions. Porous WPI/BG composites showed great potential for use as novel bone substitutes. © 2019
