Szczegóły publikacji
Opis bibliograficzny
High sensitive voltammetric determination of betamethasone on an amalgam film electrode / Joanna SMAJDOR, Beata PACZOSA-BATOR, Bogusław BAŚ, Robert PIECH // Journal of the Electrochemical Society ; ISSN 0013-4651. — 2018 — vol. 165 iss. 10, s. H646–H651. — Bibliogr. s. H650–H651
Autorzy (4)
Dane bibliometryczne
| ID BaDAP | 115496 |
|---|---|
| Data dodania do BaDAP | 2018-08-07 |
| Tekst źródłowy | URL |
| DOI | 10.1149/2.0931810jes |
| Rok publikacji | 2018 |
| Typ publikacji | artykuł w czasopiśmie |
| Otwarty dostęp |  |
| Czasopismo/seria | Journal of the Electrochemical Society |
Abstract
A voltammetric method for fast and high sensitive determination of betamethasone (BM) using an amalgam film silver based electrode (Hg(Ag)FE) was developed. Cyclic voltammetry study revealed that the BM reduction process is diffusion controlled with the participation of two electrons and two protons. In the optimum conditions, calibration curve was linear for BM in the concentration range from 5·10−9 mol L−1 (1.96·10−6 g L−1) to 0.8·10−6 mol L−1 (3.14·10−4 g L−1), with a detection limit of 1.6·10−9 mol L−1 for preconcentration time of 45 s. Repeatability of method was determined as RSD % for betamethasone concentration of 0.1·10−7 mol L−1 as 2.1% (n = 5). The proposed method was successfully applied and validated by studying the recovery of betamethasone in commercially available drugs.
