Szczegóły publikacji
Opis bibliograficzny
Novel and effective synthesis protocol of AgNPs functionalized using L-cysteine as a potential drug carrier / Marek WOJNICKI, Magdalena LUTY-BŁOCHO, Magdalena Kotańska, Magdalena WYTRWAŁ, Tomasz TOKARSKI, Anna Krupa, Marcin Kołaczkowski, Adam Bucki, Marcin Kobielusz // Naunyn-Schmiedebergs Archives of Pharmacology ; ISSN 0028-1298. — 2018 — vol. 391 iss. 2, s. 123–130. — Bibliogr. s. 129–130, Abstr. — Publikacja dostępna online od: 2017-11-16
Autorzy (9)
- AGHWojnicki Marek
- AGHLuty-Błocho Magdalena
- Kotańska Magdalena
- AGHWytrwał Magdalena
- AGHTokarski Tomasz
- Krupa Anna
- Kołaczkowski Marcin
- Bucki Adam
- Kobielusz Marcin
Słowa kluczowe
Dane bibliometryczne
| ID BaDAP | 112905 |
|---|---|
| Data dodania do BaDAP | 2018-03-26 |
| Tekst źródłowy | URL |
| DOI | 10.1007/s00210-017-1440-x |
| Rok publikacji | 2018 |
| Typ publikacji | artykuł w czasopiśmie |
| Otwarty dostęp |  |
| Creative Commons | |
| Czasopismo/seria | Naunyn-Schmiedebergs Archives of Pharmacology |
Abstract
In this study, the protocol of a single-step l-cysteine functionalized silver nanoparticle synthesis was described. Particle size distribution was determined. The crystallinity and chemical properties were investigated using XRD, HR-TEM, and XPS methods. Acute toxicity and irritant properties of obtained nanoparticles were studied using mice and rats as an animal model. The results showed that thanks to the applied protocol, it was possible to synthesize silver nanoparticles with narrow particle size distribution. Moreover, the concentration of final product was extremely high in comparison to other known methods. These nanoparticles showed neither irritant properties nor acute toxicity.