Szczegóły publikacji
Opis bibliograficzny
Facile and very sensitive electrochemical method for evaluating the release kinetics of caffeine from bioactive polymeric scaffolds / Agnieszka GRZYBOWSKA, Jakub MARCHEWKA, Ewelina Maślanka, Jadwiga LASKA, Władysław W. KUBIAK, Bogusław BAŚ // Journal of the Electrochemical Society ; ISSN 0013-4651. — 2018 — vol. 165 iss. 3, s. E89–E96. — Bibliogr. s. E96. — Publikacja dostępna online od: 2018-02-07
Autorzy (6)
Dane bibliometryczne
| ID BaDAP | 112535 |
|---|---|
| Data dodania do BaDAP | 2018-03-05 |
| Tekst źródłowy | URL |
| DOI | 10.1149/2.0191803jes |
| Rok publikacji | 2018 |
| Typ publikacji | artykuł w czasopiśmie |
| Otwarty dostęp |  |
| Czasopismo/seria | Journal of the Electrochemical Society |
Abstract
In the presented research facile, sensitive and accurate electrochemical method i.e. differential pulse voltammetry is described for evaluating the release kinetics of caffeine (CAF) from 3D bioactive polymeric scaffolds with application in bone tissue engineering. For the preparation of composite filaments (polylactide - caffeine) in a mass ratio 9:1 and 3D scaffolds Filastruder v1.0 extruder and RepRapPro Tricolor Mendel 3D printer were applied. All produced 3D structures fully reproduce virtual models. The amounts of caffeine released from filaments and scaffolds were analyzed for 96 h in deionized water, 0.1 mol · L−1 phosphate buffer saline (PBS, pH 7.4) and 0.1 mol · L−1 HCl. UV-Vis spectrophotometry was used as a reference method according to the recommendation of European pharmacopoeia (9th ed., 2016). For both methods selectivity, sensitivity, precision and accuracy were specified. Differential pulse voltammetry technique has proved to be competitive and to have high sensitivity, greater range of linearity, short analysis time, easy operation and low cost meeting the requirements of green analytical chemistry contrary to UV-Vis spectrophotometry. © The Electrochemical Society
