Szczegóły publikacji
Opis bibliograficzny
The effect of titanium dioxide addition on physical and biological properties of $Na_{2}O-B_{2}O_{3}-P_{2}O_{5}$ and $CaO-Na_{2}O-P_{2}O_{5}$ glasses / Oliwia Kalwasińska, Marcin Gajc, Andrzej Kłos, Krzysztof Orliński, Dorota A. Pawlak, Małgorzata KROK-BORKOWICZ, Łucja RUMIAN, Krzysztof PIETRYGA, Katarzyna RECZYŃSKA, Elżbieta PAMUŁA // Inżynieria Biomateriałów = Engineering of Biomaterials / Polskie Stowarzyszenie Biomateriałów ; ISSN 1429-7248. — 2016 — R. 19 nr 134, s. 2–7. — Bibliogr. s. 7, Abstr.
Autorzy (10)
- Kalwasińska Oliwia
- Gajc Marcin
- Kłos Andrzej
- Orliński Krzysztof
- Pawlak Dorota A.
- AGHKrok-Borkowicz Małgorzata
- AGHRumian Łucja Dobromiła
- AGHPietryga Krzysztof
- AGHReczyńska-Kolman Katarzyna
- AGHPamuła Elżbieta
Słowa kluczowe
Dane bibliometryczne
| ID BaDAP | 99133 |
|---|---|
| Data dodania do BaDAP | 2016-07-13 |
| Tekst źródłowy | URL |
| Rok publikacji | 2016 |
| Typ publikacji | artykuł w czasopiśmie |
| Otwarty dostęp |  |
| Creative Commons | |
| Czasopismo/seria | Inżynieria Biomateriałów = Engineering of Biomaterials |
Abstract
Two types of phosphate glasses 50Na2O-20B2O3-30P2O5 (NBP) and 30CaO-20Na2O-50P2O5 (CNP) with different content of TiO2 (0, 3 and 5 mol%) have been prepared by melt-quenching process. TiO2 was added to increase glass network stability. Physical properties of glasses were investigated by density measurements, differential scanning calorimetry and degradation in phosphate buffered saline (PBS). Biological performance of glasses in a direct contact with osteoblast-like MG-63 cells was analysed with the use of resazurin test and live-dead staining. The results show that TiO2 additionincreased density, glass transition temperature (Tg) and melting temperature (Tm) of both types of glasses. In the case of NBP glasses presence of TiO2 resulted in their fast degradation in PBS and acidification of cell culture medium. As a consequence such glasses did not support cell adhesion and growth, but they can be considered for e.g. drug delivery systems. On the other hand addition of TiO2 to CNP glasses resulted in enhanced cell adhesion and viability. Particularly positive results were found for CNP glass containing 5% TiO2, so it can be a good candidate as a scaffold material for bone tissue engineering.
