Szczegóły publikacji
Opis bibliograficzny
Elemental changes in the hippocampal formation following two different formulas of ketogenic diet: an X-ray fluorescence microscopy study / J. CHWIEJ, A. PATULSKA, A. SKOCZEŃ, K. Janeczko, M. Ciarach, R. Simon, Z. Setkowicz // Journal of Biological Inorganic Chemistry ; ISSN 0949-8257 . — 2015 — vol. 20 iss. 8, s. 1277–1286. — Bibliogr. s. 1285–1286, Abstr. — Publikacja dostępna online od: 2015-11-04
Autorzy (7)
- AGHChwiej Joanna
- AGHPatulska Agnieszka
- AGHDróżdż Agnieszka
- Janeczko Krzysztof
- Ciarch M.
- Simon R.
- Setkowicz Zuzanna
Słowa kluczowe
Dane bibliometryczne
| ID BaDAP | 95427 |
|---|---|
| Data dodania do BaDAP | 2016-02-04 |
| Tekst źródłowy | URL |
| DOI | 10.1007/s00775-1306-y |
| Rok publikacji | 2015 |
| Typ publikacji | artykuł w czasopiśmie |
| Otwarty dostęp |  |
| Creative Commons | |
| Czasopismo/seria | Journal of Biological Inorganic Chemistry |
Abstract
The main purpose of the following study was the determination of elemental changes occurring within hippocampal formation as a result of high-fat and carbohydrate-restricted ketogenic diet (KD). To realize it, X-ray fluorescence microscopy was applied for topographic and quantitative analysis of P, S, K, Ca, Fe, Cu, Zn and Se in hippocampal formations taken from rats fed with two different KDs and naive controls. The detailed comparisons were done for sectors 1 and 3 of the Ammon’s, the dentate gyrus and hilus of dentate gyrus. The results of elemental analysis showed that the KDs induced statistically significant changes in the accumulation of P, K, Ca, Zn and Se in particular areas of hippocampal formation and these alterations strongly depended on the composition of the diets. Much greater influence on the hippocampal areal densities of examined elements was found for the KD which was characterized by a lower content of carbohydrates, higher content of fats and increased proportion of unsaturated fatty acids. The levels of P, K and Zn decreased whilst those of Ca and Se increased as a result of the treatment with the KDs.
