Szczegóły publikacji
Opis bibliograficzny
Biomimetic mineralization of hydrogel biomaterials for bone tissue engineering / Timothy E. L. Douglas, Elżbieta PAMUŁA, Sander C. G. Leeuwenburgh // W: Biomimetics : advancing nanobiomaterials and tissue engineering / ed. by Murugan Ramalingam, [et al.]. — United States of America : Scrivener Publishing LLC ; Wiley, cop. 2013. — (Biomedical Science, Engineering and Technology / series ed. Murugan Ramalingam). — ISBN: 9781118469620; e-ISBN: 9781118810408. — S. 51–67. — Bibliogr. s. 63–67, Abstr. — Publikacja dostępna online od: 2013-07-31
Autorzy (3)
- Douglas Timothy E. L.
- AGHPamuła Elżbieta
- Leeuwenburgh Sander C. G.
Słowa kluczowe
Dane bibliometryczne
| ID BaDAP | 80017 |
|---|---|
| Data dodania do BaDAP | 2014-02-25 |
| DOI | 10.1002/9781118810408.ch3 |
| Rok publikacji | 2013 |
| Typ publikacji | fragment książki |
| Otwarty dostęp |  |
| Czasopismo/seria | Biomedical Science, Engineering and Technology |
Abstract
Hydrogels, or three-dimensional polymer networks with entrapped water, are gaining interest as tissue engineering scaffolds due to advantages including injectability, exact fitting to the defect site and ease of incorporation of bioactive substances and cells. For bone regeneration, however, hydrogels lack the capacity to calcify which limits their suitability for hard tissue regeneration. This chapter will review biomimetic approaches to mineralize synthetic and natural hydrogels for bone regeneration. Particular attention will be devoted to generation of extra nucleation sites by addition of ceramic nanoparticles, biomimetic mineralization in calcium- and/or phosphate-containing solutions, functionalization with calcium- and phosphate-binding species in the form of biomolecules and functional groups as well as enzymatically induced mineralization.
