Szczegóły publikacji
Opis bibliograficzny
Assessment of the lactide-co-glycolide and its composite degradation velocity under in vitro and in vivo conditions / J. CHŁOPEK, A. MORAWSKA-CHOCHÓŁ // Advances in Materials Science / Gdańskie Towarzystwo Naukowe ; ISSN 1730-2439. — 2007 — vol. 7 no. 2, s. 86–91. — Bibliogr. s. 91, Abstr.
Autorzy (2)
Dane bibliometryczne
| ID BaDAP | 37799 |
|---|---|
| Data dodania do BaDAP | 2008-03-04 |
| Rok publikacji | 2007 |
| Typ publikacji | artykuł w czasopiśmie |
| Otwarty dostęp |  |
| Czasopismo/seria | Advances in Materials Science |
Abstract
The aim of this work was the analysis of the modifying phase effect (hydroxyapatite particles and carbon fibres) and environment role (in vitro and in vivo) on mechanism and velocity of the resorption process of polylactide-co-glycolide (PGLA). Resorption time of samples incubated in simulated biological environment was determined on the basis of pH changes of the Ringer's solution. Scanning electron microscopy and infrared spectroscopy were applied for the estimation of the resorption degree of the polymer. It was observed that carbon fibres addition accelerates distinctly in vitro matrix degradation, whereas in the natural biological environment fibres reduce this time. In the case of composite with hydroxyapatite nanoparticles the in vitro processes are complex and difficult to explain. In this case simultaneous occurrence of three processes is possible: polymer resorption, HAP precipitation and dissolution. In the biological environment reduce polymer resorption time is no-ticeable.
