Szczegóły publikacji

Opis bibliograficzny

Polysaccharide hydrogels doped with MXenes for possible biomedical applications / Katarzyna SUCHOROWIEC, Justyna Kasznik, Anastasiia Stepura, Mária Omastová, Kinga PIELICHOWSKA // Molecules [Dokument elektroniczny]. — Czasopismo elektroniczne ; ISSN  1420-3049 . — 2026 — vol. 31 iss. 1 art. no. 148, s. 1-21. — Wymagania systemowe: Adobe Reader. — Bibliogr. s. 19-21, Abstr. — Publikacja dostępna online od: 2026-01-01

Autorzy (5)

Słowa kluczowe

hydrogelspolysaccharidesgellan gumMXenesodium alginiatesmart biomaterials

Dane bibliometryczne

ID BaDAP165814
Data dodania do BaDAP2026-02-23
Tekst źródłowyURL
DOI10.3390/molecules31010148
Rok publikacji2026
Typ publikacjiartykuł w czasopiśmie
Otwarty dostęptak
Creative Commons
Czasopismo/seriaMolecules

Abstract

MXenes, a new family of two-dimensional transition-metal carbides and nitrides, have attracted significant interest in biomedicine because of their tunable surface groups and multifunctional properties. Hydrogels, with their three-dimensional polymeric networks rich in water, provide excellent biocompatibility and structural similarity to those of biological tissues. Although synthetic polymer–based MXene hydrogels are well studied, polysaccharide-based systems remain underexplored despite their biodegradability and biomedical relevance. In this work, MXene nanosheets were incorporated into a sodium alginate (ALG)–gellan gum (GG) polymeric blend to develop polysaccharide/MXene hydrogels. Two dehydration approaches, conventional drying and freeze-drying were used to evaluate their influence on the characteristics of the composite, including microstructure, surface roughness, compressive behavior, water states, and thermal stability. Conventionally dried polysaccharide/MXene nanocomposites with 1.0% wt. MXene have reduced the swelling ratio by ~60% and the volume change by 40% compared to polysaccharide blend. Freeze-dried polysaccharide/MXene nanocomposite hydrogels developed a porous, interconnected network, making them promising for applications requiring high surface area, such as adsorption and tissue engineering. In contrast, conventionally dried samples formed compact, smooth structures with improved barrier and mechanical performance. These results demonstrate that the dehydration strategy strongly governs the polymer network architecture, water states, and material functionality, offering pathways to tailor hydrogel modified with MXene for specific biomedical applications.

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