Szczegóły publikacji
Opis bibliograficzny
Antibacterial metal ions doped in titanium dioxide sol-gel coatings: which offers the best performance for biomedical applications? / Barbara Burnat, Aneta Kisielewska, Mateusz MARZEC, Witold Jakubowski, Witold Szymański, Małgorzata KROK-BORKOWICZ, Elżbieta PAMUŁA // Ceramics International ; ISSN 0272-8842 . — Tytuł poprz.: Ceramurgia International ; ISSN: 0390-5519. — 2025 — vol. 51 iss. 20 pt. B, s. 31618–31631. — Bibliogr. s. 31629–31631, Abstr. — Publikacja dostępna online od: 2025-04-25
Autorzy (7)
- Burnat Barbara
- Kisielewska Aneta
- AGHMarzec Mateusz M.
- Jakubowski Witold
- Szymański Witold
- AGHKrok-Borkowicz Małgorzata
- AGHPamuła Elżbieta
Słowa kluczowe
Dane bibliometryczne
| ID BaDAP | 161892 |
|---|---|
| Data dodania do BaDAP | 2025-09-04 |
| Tekst źródłowy | URL |
| DOI | 10.1016/j.ceramint.2025.04.353 |
| Rok publikacji | 2025 |
| Typ publikacji | artykuł w czasopiśmie |
| Otwarty dostęp |  |
| Czasopismo/seria | Ceramics International |
Abstract
Despite the growing interest in antibacterial metal-doped ceramic coatings, direct comparisons of different dopants under standardized synthesis and testing conditions remain limited. This study addresses that gap by presenting a systematic evaluation of four commonly used antibacterial dopants — Ag, Cu, Ga, and Zn metal ions — incorporated into titanium dioxide (TiO2) coatings via a sol–gel method. The coatings, featuring an anatase structure and consistent dopant concentrations, were deposited on M30NW biomedical alloy. A comprehensive characterization was conducted using XPS, SEM, AFM, nanoindentation, scratch testing, and water contact angle measurements to assess chemical composition, surface morphology, roughness, hardness, adhesion, and wettability. Corrosion resistance in phosphate−buffered saline (PBS) was evaluated using linear polarization resistance and potentiodynamic polarization techniques. Cytocompatibility was investigated through pre-osteoblast viability, proliferation, and morphology assays, along with osteogenic differentiation of mesenchymal stem cells. Antibacterial activity against Escherichia coli and Streptococcus mutans was assessed based on biofilm formation and bacterial viability. The findings highlight the strong biomedical potential of metal ion–doped TiO2 coatings. Notably, Ga-doped coatings exhibited the most favorable balance of properties, combining robust antibacterial activity (comparable to Ag), enhanced corrosion resistance, and superior osteogenic potential — making them particularly suitable for bone implant applications.
