Szczegóły publikacji
Opis bibliograficzny
Diagnostic value of the standardised uptake value (SUV) ratio of mediastinal lymph node to primary tumour in lung cancer / Błażej Kużdżał, Adam Kużdżał, Karolina Gambuś, Adam ĆMIEL, Konrad Moszczyński, Sofiia Popovchenko, Monika Bryndza, Lucyna Rudnicka, Katarzyna Żanowska, Łukasz Trybalski, Janusz Warmus, Piotr Kocoń // Polish Journal of Radiology ; ISSN 1733-134X. — 2025 — vol. 90, s. 97–102. — Bibliogr. s. 101–102, Abstr. — Publikacja dostępna online od: 2025-02-18
Autorzy (12)
- Kużdżał Błażej
- Kużdżał Adam
- Gambuś Karolina
- AGHĆmiel Adam
- Moszczyński Konrad
- Popovchenko Sofiia
- Bryndza Monika
- Rudnicka Lucyna
- Żanowska Katarzyna
- Trybalski Łukasz
- Warmus Janusz
- Kocoń Piotr
Słowa kluczowe
Dane bibliometryczne
| ID BaDAP | 159829 |
|---|---|
| Data dodania do BaDAP | 2025-06-16 |
| Tekst źródłowy | URL |
| DOI | 10.5114/pjr/200009 |
| Rok publikacji | 2025 |
| Typ publikacji | artykuł w czasopiśmie |
| Otwarty dostęp |  |
| Creative Commons | |
| Czasopismo/seria | Polish Journal of Radiology |
Abstract
Purpose: This study aimed to determine whether the mediastinal lymph node/tumour ratio (NTR) of the standardised uptake value (SUV) predicts N2 involvement more accurately than node SUV in patients with non-small cell lung cancer (NSCLC). Material and methods: We retrospectively analysed consecutive patients with lung cancer at clinical stages I-IVA. All patients underwent positron emission tomography-computed tomography (PET-CT), followed by mediastinal staging using endobronchial ultrasound and endoscopic ultrasound imaging, and curative-intent lung resection with systematic lymph node dissection. Pathological examination of the surgical specimen was performed for confirmation. Results: The data from 774 patients were analysed. There was a significant correlation between the risk of false-negative PET results for N2 disease and both the SUV of the mediastinal nodes (p = 0.012) and NTR (p = 0.030). The NTR outperformed node SUV in predictive ability; the Akaike information criterion was 307.268 for NTR compared to 308.498 for node SUV. Three factors were significantly associated with the positive predictive value of PET: patient age (p = 0.021), female sex (p = 0.012), and adenocarcinoma histology (p = 0.036). There were no significant correlations between PET sensitivity, specificity, and negative predictive value (NPV), and age, sex, body mass index (BMI), tumour grade, lobar location, or histological type. Conclusions: The NTR may be a useful tool for excluding N2 disease in NSCLC. PET sensitivity and NPV for detecting N2 disease are not influenced by age, sex, BMI, tumour grade, lobar location, or histological type.
