Szczegóły publikacji
Opis bibliograficzny
Hydrogel dressing biomaterial enriched with vitamin C: synthesis and characterization / Piotr SZATKOWSKI, Zuzanna Flis, Anna Ptak, Edyta Molik // International Journal of Molecular Sciences [Dokument elektroniczny]. — Czasopismo elektroniczne ; ISSN 1422-0067 . — 2024 — vol. 25 iss. 19 art. no. 10565, s. 1–19. — Wymagania systemowe: Adobe Reader. — Bibliogr. s. 18–19, Abstr. — Publikacja dostępna online od: 2024-09-30
Autorzy (4)
- AGHSzatkowski Piotr
- Flis Zuzanna
- Ptak Anna
- Molik Edyta
Słowa kluczowe
Dane bibliometryczne
| ID BaDAP | 155864 |
|---|---|
| Data dodania do BaDAP | 2024-10-31 |
| Tekst źródłowy | URL |
| DOI | 10.3390/ijms251910565 |
| Rok publikacji | 2024 |
| Typ publikacji | artykuł w czasopiśmie |
| Otwarty dostęp |  |
| Creative Commons | |
| Czasopismo/seria | International Journal of Molecular Sciences |
Abstract
Materials engineering has become an important tool in the field of hydrogel dressings used to treat difficult-to-heal wounds. Hydrogels filled with bioactive substances used as a targeted healing system are worthy of attention. Vitamin C has healing and supporting effects in the treatment of many skin problems. The aim of the research was to produce a hydrogel biomaterial enriched with ascorbic acid for use as a dressing for difficult-to-heal wounds. A total of four different dressings were developed, each with different modifications in each layer. The dressing with vitamin C in the third layer was shown to release vitamin C ions more slowly than the dressing with vitamin C in the first layer. The studies conducted have shown that the dressings containing vitamin C have, among other things, a higher compressive strength, are characterised by a lower relative shortening after the application of force and shorten without damage at a lower force than in the case of a dressing without vitamin C. The dressings designed have a very good stability in the temperature range of 18 °C to 60 °C. It was found that the higher the vitamin C content in the dressing, the greater the increase in the specific heat value of the transformations. Therefore, hydrogel dressings containing vitamin C may be candidates for local delivery of vitamin C to the skin and protection of the wound area.
