Szczegóły publikacji
Opis bibliograficzny
Exploring CVD method for synthesizing carbon–carbon composites as materials to contact with nerve tissue / Aneta FRĄCZEK-SZCZYPTA, Natalia Kondracka, Marcel ZAMBRZYCKI, Maciej GUBERNAT, Paweł Czaja, Mirosława Pawlyta, Piotr JELEŃ, Ryszard WIELOWSKI, Danuta Jantas // Journal of Functional Biomaterials [Dokument elektroniczny]. — Czasopismo elektroniczne ; ISSN 2079-4983. — 2023 — vol. 14 iss. 9 art. no. 443, s. 1–27. — Wymagania systemowe: Adobe Reader. — Bibliogr. s. 24–27, Abstr. — Publikacja dostępna online od: 2023-08-28
Autorzy (9)
- AGHFrączek-Szczypta Aneta
- AGHKondracka Natalia
- AGHZambrzycki Marcel
- AGHGubernat Maciej
- Czaja Paweł
- Pawlyta Mirosława
- AGHJeleń Piotr
- AGHWielowski Ryszard
- Jantas Danuta
Słowa kluczowe
Dane bibliometryczne
| ID BaDAP | 148402 |
|---|---|
| Data dodania do BaDAP | 2023-09-06 |
| Tekst źródłowy | URL |
| DOI | 10.3390/jfb14090443 |
| Rok publikacji | 2023 |
| Typ publikacji | artykuł w czasopiśmie |
| Otwarty dostęp |  |
| Creative Commons | |
| Czasopismo/seria | Journal of Functional Biomaterials |
Abstract
The main purpose of these studies was to obtain carbon–carbon composites with a core built of carbon fibers and a matrix in the form of pyrolytic carbon (PyC), obtained by using the chemical vapor deposition (CVD) method with direct electrical heating of a bundle of carbon fibers as a potential electrode material for nerve tissue stimulation. The methods used for the synthesis of PyC proposed in this paper allow us, with the appropriate selection of parameters, to obtain reproducible composites in the form of rods with diameters of about 300 µm in 120 s (CF_PyC_120). To evaluate the materials, various methods such as scanning electron microscopy (SEM), scanning transmission electron microscope (STEM), high-resolution transmission electron microscopy (HRTEM), selected area electron diffraction (SAED), Raman spectroscopy, X-ray photoelectron spectroscopy (XPS), and tensiometer techniques were used to study their microstructural, structural, chemical composition, surface morphology, and surface wettability. Assessing their applicability for contact with nervous tissue cells, the evaluation of cytotoxicity and biocompatibility using the SH-SY5Y human neuroblastoma cell line was performed. Viability and cytotoxicity tests (WST-1 and LDH release) along with cell morphology examination demonstrated that the CF_PyC_120 composites showed high biocompatibility compared to the reference sample (Pt wire), and the best adhesion of cells to the surface among all tested materials.
