Szczegóły publikacji
Opis bibliograficzny
High sensitivity and selectivity microwave biosensor using biofunctionalized differential resonant array implemented in LTCC for Escherichia coli detection / Ilona PIEKARZ, Jakub SOROCKI, Sabina Górska, Heike Bartsch, Artur RYDOSZ, Robert SMOLARZ, Krzysztof WINCZA, Sławomir GRUSZCZYŃSKI // Measurement ; ISSN 0263-2241. — 2023 — vol. 208 art. no. 112473, s. 1–8. — Bibliogr. s. 8, Abstr. — Publikacja dostępna online od: 2023-01-11
Autorzy (8)
Słowa kluczowe
Dane bibliometryczne
| ID BaDAP | 146479 |
|---|---|
| Data dodania do BaDAP | 2023-05-10 |
| Tekst źródłowy | URL |
| DOI | 10.1016/j.measurement.2023.112473 |
| Rok publikacji | 2023 |
| Typ publikacji | artykuł w czasopiśmie |
| Otwarty dostęp |  |
| Creative Commons | |
| Czasopismo/seria | Measurement |
Abstract
A novel method for label-free detection of Escherichia coli relying on microwave sensing is proposed. A transmission-type differential resonator array biosensor covered with polyclonal anti-Escherichia coli antibodies is introduced providing a robust response with high sensitivity for detecting bacteria presence due to resonant operation combined. The high selectivity is given by the presence of specific bacteria-binding antibodies. LowTemperature Co-Fired Ceramics technology is proposed to be used for implementation to take advantage of its quasi-three-dimensional fabrication capability. The proposed sensing structure operates in a frequency range of 4 - 6 GHz with five distinct resonances increasing the probability of bacteria detection presence. The developed sensor was experimentally validated by measurements of various concentrations of Escherichia coli along with measurement of a non-specific high concentration of Lactobacillus rhamnosus LOCK 0919. The obtained results prove the performance and suitability of the proposed biosensor for biomedical applications.
