Szczegóły publikacji
Opis bibliograficzny
Aminolysis as a surface functionalization method of aliphatic polyester nonwovens: impact on material properties and biological response / Oliwia Jeznach, Dorota Kołbuk, Mateusz MARZEC, Andrzej BERNASIK, Paweł Sajkiewicz // RSC Advances [Dokument elektroniczny]. — Czasopismo elektroniczne ; ISSN 2046-2069. — 2022 — vol. 12 iss. 18, s. 11303-11317. — Wymagania systemowe: Adobe Reader. — Bibliogr. s. 11316-11317, Abstr. — Publikacja dostępna online od: 2022-04-11
Autorzy (5)
- Jeznach Oliwia
- Kołbuk Dorota
- AGHMarzec Mateusz M.
- AGHBernasik Andrzej
- Sajkiewicz Paweł Ł.
Dane bibliometryczne
| ID BaDAP | 139959 |
|---|---|
| Data dodania do BaDAP | 2022-04-22 |
| Tekst źródłowy | URL |
| DOI | 10.1039/d2ra00542e |
| Rok publikacji | 2022 |
| Typ publikacji | artykuł w czasopiśmie |
| Otwarty dostęp |  |
| Creative Commons | |
| Czasopismo/seria | RSC Advances |
Abstract
It is reported in the literature that introducing amino groups on the surface improves cellular behaviour due to enhanced wettability and the presence of the positive charge. In this work, electrospun fibers were subjected to aminolysis under various conditions to investigate the impact of reaction parameters on the concentration of free NH2 groups, change of fiber properties, and the response of L929 cells. Three types of electrospun nonwovens obtained from poly(caprolactone) (PCL), poly(l-lactide-co-caprolactone) (PLCL) 70 : 30 and poly(l-lactide) (PLLA) were investigated. For all polymers, the concentration of NH2 groups increased with the diamine concentration and time of reaction. However, it was observed that PCL fibers require much stronger conditions than PLCL and PLLA fibers to reach the same level of introduced amine groups. X-ray photoelectron spectroscopy results clearly demonstrate that an aminolysis reaction is not limited to the surface of the material. Gel permeation chromatography results support this conclusion indicating global molecular weight reduction. However, it is possible to reach a compromise between the concentration of introduced amine groups and the change of mechanical properties. For most of the investigated conditions, aminolysis did not significantly change the water contact angle. Despite this, the change of L929 and MG63 cell shape to being more spread confirmed the positive effect of the presence of the amine groups.
