Szczegóły publikacji
Opis bibliograficzny
Highly sensitive voltammetric determination of captopril on renewable amalgam film electrode / Anna GÓRSKA, Beata PACZOSA-BATOR, Marek Szlósarczyk, Robert PIECH // Talanta ; ISSN 0039-9140. — 2022 — vol. 237 art. no. 122937, s. 1–7. — Bibliogr. s. 7, Abstr. — Publikacja dostępna online od: 2021-10-06
Autorzy (4)
- AGHGórska-Ratusznik Anna
- AGHPaczosa-Bator Beata
- Szlósarczyk Marek
- AGHPiech Robert
Słowa kluczowe
Dane bibliometryczne
| ID BaDAP | 137264 |
|---|---|
| Data dodania do BaDAP | 2021-11-06 |
| Tekst źródłowy | URL |
| DOI | 10.1016/j.talanta.2021.122937 |
| Rok publikacji | 2022 |
| Typ publikacji | artykuł w czasopiśmie |
| Otwarty dostęp |  |
| Czasopismo/seria | Talanta |
Abstract
New highly sensitive voltammetric method for captopril (CPT) determination was developed. The main novelty of the work was the application of a renewable amalgam film electrode (Hg(Ag)FE) for this purpose. During the research instrumental parameters of the developed method were optimized and were as follows: tw = ts = 5 ms, Es = 5 mV, ΔE = 100 mV. Preconcentration potential and time were equal to 100 mV and 20 s, respectively. All measurements were conducted in electrolyte consisted of 0.1 M HClO4. Limit of detection was calculated and was equal to 1.9 nM (0.39 ng mL−1) for 20 s preconcentration time and Hg(Ag)FE surface area approximately 11.2 mm2. Linearity was achieved in the concentration range 0.05–1 μM. Repeatability of the method expressed as variation coefficient was estimated at 3.5% (0.15 μM CPT, n = 10). Applicability of the method was confirmed by analysis of tablets containing CPT and urine. Recoveries were in the range from 95 to 109% suggesting that the method might be assumed as accurate. Obtained results were also in good agreement with the producer declaration. © 2021 Elsevier B.V.
