Szczegóły publikacji

Opis bibliograficzny

Influence of the replacement of silica by boron trioxide on the properties of bioactive glass scaffolds / Katharina Schuhladen, Usanee Pantulap, Kristin Engel, Piotr JELEŃ, Zbigniew Olejniczak, Leena Hupa, Maciej SITARZ, Aldo R. Boccaccini // International Journal of Applied Glass Science ; ISSN 2041-1286. — 2021 — vol. 12 iss. 3, s. 293–312. — Bibliogr. s. 308–312, Abstr.

Autorzy (8)

Słowa kluczowe

structural analysisbioactive glassborateborosilicatescaffoldsbioactivity

Dane bibliometryczne

ID BaDAP135400
Data dodania do BaDAP2021-07-27
Tekst źródłowyURL
DOI10.1111/ijag.15894
Rok publikacji2021
Typ publikacjiartykuł w czasopiśmie
Otwarty dostęptak
Creative Commons
Czasopismo/seriaInternational Journal of Applied Glass Science

Abstract

The dissolution properties and bioactivity of bioactive glasses (BGs) are mainly determined by their composition and glass network structure. Silicate BGs are arguable the most popular representatives of BGs. However, borate BGs have gained increasing interest due to their faster degradation rate. By adding boron trioxide in the silicate network, borosilicate BGs can be fabricated with controlled degradation rates. Since the kind and amount of network former determines the resulting BG properties, the aim of this study was to examine the glass structure of silicate, borosilicate and borate BGs. Also, the effect of changing the network former on the ability to fabricate BG scaffolds by the foam replica method was investigated. The resulting silicate, borosilicate, and borate scaffolds were further examined on their chemical, morphological, mechanical, and bioactive properties. Structural analyses showed that the introduction of boron trioxide into silicate BGs leads to the depolymerization of the silicate network. Accordingly, the ion release profile and the ability to form hydroxyapatite of the different scaffolds were affected. Thus, this study shows that tailored BG compositions with case-specific properties can be designed and used to fabricate 3D scaffolds for potential use in bone tissue engineering.

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