Szczegóły publikacji
Opis bibliograficzny
Interactions of $\beta-carotene$ with red blood cells: its regulatory role on hemoglobin functioning / J. FIEDOR, M. PRZETOCKI, A. Siniarski, G. Gajos, N. Spiridis, K. Freindl, K. BURDA // Acta Physica Polonica. A ; ISSN 0587-4246. — 2021 — vol. 139 no. 3, s. 283–287. — Bibliogr. s. 287. — XLVI Extraordinary Congress of Polish Physicists : Warsaw, Poland, October 16–18, 2020
Autorzy (7)
- AGHFiedor Joanna
- AGHPrzetocki Mateusz
- Siniarski Aleksander
- Gajos Grzegorz
- Spiridis Nika
- Freindl Kinga
- AGHBurda Kvetoslava
Słowa kluczowe
Dane bibliometryczne
| ID BaDAP | 133385 |
|---|---|
| Data dodania do BaDAP | 2021-04-09 |
| Tekst źródłowy | URL |
| DOI | 10.12693/APhysPolA.139.283 |
| Rok publikacji | 2021 |
| Typ publikacji | referat w czasopiśmie |
| Otwarty dostęp |  |
| Creative Commons | |
| Czasopismo/seria | Acta Physica Polonica, A |
Abstract
Carotenoids are structurally and functionally a very diverse group of natural pigments. They are produced exclusively by organisms capable of photosynthesis and serve as important exogenous antioxidants for all living organisms. One of the most widespread carotenoids is β-carotene. In vitro studies demonstrated its ability to integrate with red blood cells' membranes affecting their physical and functional properties. Here, the results of experiments conducted on isolated red blood cells treated with β-carotene at concentration ~107 β-carotene/cell are presented. In particular, the Mössbauer spectroscopy was used to monitor hemoglobin states and its ability to reversibly bind oxygen in red blood cells incubated in the presence of β-carotene. The results showed that even at concentrations slightly above the physiological level (in plasma: 104-105 β-carotene/cell) β-carotene may affect not only the morphometric parameters of red blood cells but also modulate hemoglobin-oxygen affinity.
