Szczegóły publikacji
Opis bibliograficzny
Usefulness of combined endobronchial and endoscopic ultrasound-guided needle aspiration in the diagnosis of sarcoidosis: a prospective multicenter trial / Anna Filarecka, Maciej Gnass, Jacek Wojtacha, Jerzy Soja, Juliusz Pankowski, Damian Czyżewski, Wojciech Zajęcki, Arkadiusz Joks, Adam ĆMIEL, Artur Szlubowski // Polish Archives of Internal Medicine = Polskie Archiwum Medycyny Wewnętrznej [Dokument elektroniczny]. — Czasopismo elektroniczne ; ISSN 1897-9483. — 2020 — vol. 130 no. 7–8, s. 582–588. — Wymagania systemowe: Adobe Reader. — Bibliogr. s. 587–588, Abstr. — Publikacja dostępna online od: 2020-05-28
Autorzy (10)
- Filarecka Anna
- Gnass Maciej
- Wojtacha Jacek
- Soja Jerzy
- Pankowski Juliusz
- Czyżewski Damian
- Zajęcki Wojciech
- Joks Arkadiusz
- AGHĆmiel Adam
- Szlubowski Artur
Słowa kluczowe
Dane bibliometryczne
| ID BaDAP | 129973 |
|---|---|
| Data dodania do BaDAP | 2020-09-15 |
| Tekst źródłowy | URL |
| DOI | 10.20452/pamw.15399 |
| Rok publikacji | 2020 |
| Typ publikacji | artykuł w czasopiśmie |
| Otwarty dostęp |  |
| Creative Commons | |
| Czasopismo/seria | Polskie Archiwum Medycyny Wewnętrznej = Polish Archives of Internal Medicine |
Abstract
Introduction: Needle biopsy of enlarged lymph nodes is an accepted method for the diagnostic workup of sarcoidosis, but the optimal endosonography-guided approach is yet to be determined. Objectives: The aim of our study was to assess the relative diagnostic yield of combined ultrasound-guided needle aspiration (CUS-b-NA), which includes endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) with endoscopic ultrasound fine-needle aspiration (EUS-b-FNA), as well as the role of the cell block (CB) technique and lymph node localization in the diagnostic workup of sarcoidosis. Patients and methods: This was a prospective multicenter study including consecutive patients with clinical suspicion of stage I or II sarcoidosis. CUS-b-NA with smears and CB technique were performed in the whole study group. If a biopsy result was not conclusive, an invasive diagnostic workup and a 6-month follow-up were scheduled. Results: Out of 77 screened patients, 54 signed written consent and 50 were enrolled for the final analysis. The overall sensitivity of EBUS-TBNA, EUS-b-FNA, and CUS-b-NA was 76.6%, 70.2%, and 91.7%, respectively. There were no differences between EBUS-TBNA and EUS-b-FNA (P = 0.52) but CUS-b-NA had a higher diagnostic yield (P = 0.005 and P = 0.001, respectively). Adding the CB method to smear technique (P = 0.008) and biopsy of the subcarinal lymph nodes increased the diagnostic yield (P = 0.001). Conclusions: The diagnostic yield of CUS-b-NA is higher than that of endosonographic techniques alone in the diagnostic workup of stage I and II sarcoidosis. The preparation of cytological material including CB and the choice of the subcarinal lymph node station for the biopsy increase the diagnostic efficacy.
