Szczegóły publikacji
Opis bibliograficzny
A simple, low-cost and green method for controlling the cytotoxicity of MXenes / A. Rozmysłowska-Wojciechowska, A. Szuplewska, T. Wojciechowski, S. Poźniak, J. Mitrzak, M. Chudy, W. Ziemkowska, L. CHLUBNY, A. Olszyna, A. M. Jastrzębska // Materials Science and Engineering. C, Materials for Biological Applications ; ISSN 0928-4931. — 2020 — vol. 111 art. no. 110790, s. 1–8. — Bibliogr. s. 7–8, Abstr. — Publikacja dostępna online od: 2020-02-29
Autorzy (10)
- Rozmysłowska-Wojciechowska Anita
- Szuplewska Aleksandra
- Wojciechowski Tomasz
- Poźniak Szymon
- Mitrzak Joanna
- Chudy Michał
- Ziemkowska Wanda
- AGHChlubny Leszek
- Olszyna Andrzej
- Jastrzębska Agnieszka M.
Słowa kluczowe
Dane bibliometryczne
| ID BaDAP | 128129 |
|---|---|
| Data dodania do BaDAP | 2020-04-01 |
| Tekst źródłowy | URL |
| DOI | 10.1016/j.msec.2020.110790 |
| Rok publikacji | 2020 |
| Typ publikacji | artykuł w czasopiśmie |
| Otwarty dostęp |  |
| Czasopismo/seria | Materials Science and Engineering, C, Materials for Biological Applications |
Abstract
MXene phases are a member of the intriguing 2D material family, beyond graphene. They are good candidates for many applications, however, their potential toxicity is of crucial importance for future development. Herein, we present a simple, low-cost and fully green approach for controlling the potential cytotoxicity of 2D MXenes after delamination by harnessing the interactions that occur between the surface of MXene phases and natural biomacromolecule – collagen. We also demonstrate that the step-by-step adsorption and desorption of collagen from the surface of 2D MXenes is easily controlled using in situ zeta potential measurements coupled with dynamic light scattering (DLS) method. The obtained results demonstrated that the electrostatically driven unprecedented susceptibility of the MXenes' surfaces to collagen. Surface-modification reduces toxicity of MXenes in vitro i.e. adjust cells' viabilities as well as reduce their oxidative stress. This indicates enhanced biocompatibility of 2D Ti3C2 and Ti2C MXenes surface-modified with collagen, which is involved in many bio-interactions as important building blocks in the human body. The presented study opens new avenues for designing MXenes with defined surface properties and paves the way for their future successful management in nano-medicinal applications. © 2020
