Szczegóły publikacji
Opis bibliograficzny
Examining the influence of functionalized POSS on the structure and bioactivity of flexible polyurethane foams / Edyta Hebda, Artur Bukowczan, Sławomir Michałowski, Sebastian WROŃSKI, Paulina Urbaniak, Mariusz Kaczmarek, Emilia Hutnik, Aleksandra Romaniuk, Maria Wolun-Cholewa, Krzysztof Pielichowski // Materials Science and Engineering. C, Materials for Biological Applications ; ISSN 0928-4931. — 2020 — vol. 108 art. no. 110370, s. 1-12. — Bibliogr. s. 11–12, Abstr. — Publikacja dostępna online od: 2019-11-02
Autorzy (10)
- Hebda Edyta
- Bukowczan Artur
- Michałowski Sławomir
- AGHWroński Sebastian
- Urbaniak Paulina
- Kaczmarek Mariusz T.
- Hutnik Emilia
- Romaniuk Aleksandra
- Wolun-Cholewa Maria
- Pielichowski Krzysztof
Słowa kluczowe
Dane bibliometryczne
| ID BaDAP | 126068 |
|---|---|
| Data dodania do BaDAP | 2020-01-20 |
| Tekst źródłowy | URL |
| DOI | 10.1016/j.msec.2019.110370 |
| Rok publikacji | 2020 |
| Typ publikacji | artykuł w czasopiśmie |
| Otwarty dostęp |  |
| Czasopismo/seria | Materials Science and Engineering, C, Materials for Biological Applications |
Abstract
This work reports for the first time on a new class of flexible polyurethane foam hybrids (PUFs) synthesized with the use of less toxic aliphatic hexamethylene diisocyanate (HDI), which have been chemically modified by POSS moieties. The flexible polyurethane foam hybrids (PUFs) chemically modified by functionalized polyhedral oligomeric silsesquioxanes: octa(3-hydroxy-3-methylbutyldimethylsiloxy)POSS (OCTA-POSS) and 1,2-propanediolizo-butylPOSS (PHI-POSS), was obtained. The resulting foams, which contain 0 to 15 wt % POSS, were characterized in terms of their structure, morphology, density and compressive strength. The FT-IR results indicate the chemical incorporation of both OCTAPOSS and PHIPOSS into the polyurethane matrix. SEM-EDS analysis showed that both OCTAPOSS and PHIPOSS nanoparticles are distributed homogeneously in the foam structure; at 15 wt % load PHIPOSS characteristic “crosses” are formed. With the increase of PHIPOSS content in the matrix, the formation of agglomerates is observed, as revealed by WAXD spectra. The introduction of POSS compounds reduces the porosity of the polyurethane, with the number of pores increasing as the amount of modifier increases. Mechanical tests - compressive strength - show that the hardness of modified materials (5 wt % POSS) increases compared to the reference material. An incubation was carried out in a simulated physiological fluid (SBF) to pre-assess the bioactivity of the materials obtained. The obtained results confirmed the formation of a hydroxyapatite layer on the PUF-POSS surface. Cytotoxicity, cell cycle and apoptosis of osteoblast cells and fibroblasts were assessed in the presence of the PUF-POSS materials. Test materials have a cytotoxic effect on both established cell lines. PUF-PHIPOSS samples showed better biocompatibility than reference and PUF-OCTAPOSS samples, as they caused lower mortality of the examined cells.
