Szczegóły publikacji
Opis bibliograficzny
Gel-derived materials of a $CaO-P_{2}O_{5}-SiO_{2}$ system modified by boron, sodium, magnesium, aluminum, and fluorine compounds / Maria ŁĄCZKA, Katarzyna CHOLEWA-KOWALSKA, Anna Łączka-Osyczka, Magdalena Tworzydlo, Bogdan Turyna // Journal of Biomedical Materials Research ; ISSN 0021-9302. — 2000 — vol. 52 iss. 4, s. 601–612. — Bibliogr. s. 612, Abstr.
Autorzy (5)
- AGHBorczuch-Łączka Maria
- AGHCholewa-Kowalska Katarzyna
- Łączka-Osyczka Anna
- Tworzydło Magdalena
- Turyna Bogdan
Słowa kluczowe
Dane bibliometryczne
| ID BaDAP | 12165 |
|---|---|
| Data dodania do BaDAP | 2003-03-10 |
| Tekst źródłowy | URL |
| Rok publikacji | 2000 |
| Typ publikacji | artykuł w czasopiśmie |
| Otwarty dostęp |  |
| Czasopismo/seria | Journal of Biomedical Materials Research |
Abstract
Bioactive glass-ceramic materials of the CaO-P2O5-SiO2 system modified by adding boron, magnesium, sodium, fluorine, and aluminum were obtained using the sol-gel method. Gel-derived materials were produced in the pellet form obtained by compression of powders as well as in coatings on glass slides. The materials obtained were examined in vitro with regard to the ability of calcium phosphate layer to form on the material surface as the result of contact with simulated body fluid (SBF). SBF pH changes and calcium solubility in this solution were determined and scanning electron microscopy, energy-dispersive X-ray analysis, and infrared spectroscopy studies were conducted before and after contact of the materials with SBF. The gels modified by aluminum were amorphous, whereas the sodium and fluorine additives promoted the bulk crystallization of gel-derived materials. The ability of calcium phosphates to crystallize on the surface of gel-derived materials depended only slightly on the types of additives applied, and the character of this dependence was different from that observed in melted glasses. Moreover, to estimate the biocompatibility of gel-derived coatings, we examined the proliferation, collagen synthesis, adhesion, and morphology of fibroblasts (NRK cells) cultured in the presence of gel-derived materials. The results of these experiments showed that none of the tested materials significantly reduced any cell function.
