Szczegóły publikacji
Opis bibliograficzny
Saphenous graft atherosclerosis as assessed by optical coherence tomography data for stenotic and non-stenotic lesions from the OCTOPUS registry / Grzegorz M. Kubiak, Elżbieta Pociask, Wojciech Wańha, Magdalena Dobrolińska, Paweł Gąsior, Grzegorz Smolka, Andrzej Ochała, Zbigniew Gąsior, Wojciech Wojakowski, Tomasz Roleder // Advances in Interventional Cardiology = Postępy w Kardiologii Interwencyjnej ; ISSN 1734-9338. — 2018 — vol. 14 iss. 2, s. 157–166. — Bibliogr. s. 165–166, Abstr. — Publikacja dostępna online od: 2018-06-19. — E. Pociask - afiliacja: Krakow Cardiovascular Research Institute, Jagiellonian University Medical College, Krakow
Autorzy (10)
- Kubiak Grzegorz M.
- Pociask Elżbieta
- Wańha Wojciech
- Dobrolińska Magdalena
- Gąsior Paweł
- Smolka Grzegorz
- Ochała Andrzej
- Gąsior Zbigniew
- Wojakowski Wojciech
- Roleder Tomasz
Słowa kluczowe
Dane bibliometryczne
| ID BaDAP | 120945 |
|---|---|
| Data dodania do BaDAP | 2019-04-17 |
| Tekst źródłowy | URL |
| DOI | 10.5114/aic.2018.76407 |
| Rok publikacji | 2018 |
| Typ publikacji | artykuł w czasopiśmie |
| Otwarty dostęp |  |
| Creative Commons | |
| Czasopismo/seria | Postępy w Kardiologii Interwencyjnej = Advances in Interventional Cardiology |
Abstract
Introduction: Coronary artery bypass grafting (CABG), although widely used for a long time in diffuse coronary artery disease (CAD), has serious limitations associated with graft aging and its degeneration. Aim: The relationship between saphenous vein graft (SVG) plaque morphology assessed by optical coherence tomography (OCT) and clinical findings has not been elucidated yet. Material and methods: We compared the morphology of SVG in stenotic vs. non-stenotic lesions using OCT imaging in 29 patients hospitalized in our center within the OCTOPUS registry. Results: Stenotic lesions were characterized by higher incidence of thin-cap fibroatheroma (TCFA) (33% vs. 0%, p = 0.0048), thrombus (28% vs. 0%, p = 0.0008), lipid-rich plaque (LRP) (75% vs. 35%, p = 0.0013) and plaque within the SVG valve (19% vs. 0%, p = 0.0114) as compared to non-stenotic lesions. Patients with intimal tearing or rupture (ITR) were older (75.8% vs. 68.9 years, p = 0.047) and had lower left ventricular ejection fraction (LVEF) (32.0% vs. 49.7%, p = 0.001) and glomerular filtration rate (GFR) (36.0 vs. 73.6 ml/min/1.73 m(2), p = 0.010). Patients with calcified lesions vs. those without had lower high-density lipoprotein (HDL) cholesterol (33.2 vs. 44.1 mg/dl, p = 0.018), similarly to those with ruptured plaque vs. those without (28.3 vs. 41.7 mg/dl, p = 0.047). Conclusions: Presence of ITR was associated with advanced age, decreased LVEF and renal insufficiency. Decreased concentration of HDL was associated with higher occurrence of calcified and ruptured plaque.
