Szczegóły publikacji
Opis bibliograficzny
Biological effect of hydrothermally synthesized silica nanoparticles within crystalline hydroxyapatite coatings for titanium implants / Amanda Bartkowiak, Katarzyna Suchanek, Elżbieta Menaszek, Barbara SZARANIEC, Janusz Lekki, Marcin Perzanowski, Marta Marszałek // Materials Science and Engineering. C, Biomimetic Materials, Sensors and Systems ; ISSN 0928-4931. — 2018 — vol. 92, s. 88–95. — Bibliogr. s. 94–95, Abstr. — Publikacja dostępna online od: 2018-06-19
Autorzy (7)
- Bartkowiak Amanda
- Suchanek Katarzyna
- Menaszek Elżbieta
- AGHSzaraniec Barbara
- Lekki Janusz
- Perzanowski Marcin
- Marszałek Marta J.
Słowa kluczowe
Dane bibliometryczne
| ID BaDAP | 115325 |
|---|---|
| Data dodania do BaDAP | 2018-07-31 |
| Tekst źródłowy | URL |
| DOI | 10.1016/j.msec.2018.06.043 |
| Rok publikacji | 2018 |
| Typ publikacji | artykuł w czasopiśmie |
| Otwarty dostęp |  |
| Czasopismo/seria | Materials Science and Engineering, C, Materials for Biological Applications |
Abstract
Development of functional coatings for artificial bone implants that strengthen the osseointegration and accelerate bone healing processes is urgently needed in the biomedical field. In this study we present biological effect of novel composite coatings with different concentration of silica nanoparticles within crystalline hydroxyapatite matrix (HAp-SiO2) synthesized on titanium under hydrothermal conditions. Samples were analyzed for their elemental composition, structure, bioactivity and in vitro cytotoxicity. The results indicate the formation and homogeneous distribution of silica nanoparticles on the surface of hexagonal hydroxyapatite (HAp) crystals. The coatings show improved bioactivity in comparison with pure HAp after 4 days of immersion in simulated body fluid (SBF). The responses of human osteoblast-like cells (MG-63) cultured onto the synthesized materials provide evidence that HAp-SiO2 composites exhibit good biocompatibility. We propose that this is because HAp-SiO2 composites favor biomineralization process with cell proliferation remaining unaffected, regardless of the amount of silica. Furthermore, SEM and fluorescence measurements demonstrate that HAp-SiO2 had positive effect on cell morphology, favoring cell adhesion.
