Szczegóły publikacji
Opis bibliograficzny
Hydroxyapatite-chitosan based bioactive hybrid biomaterials with improved mechanical strength / A. ZIMA // Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy ; ISSN 1386-1425. — 2018 — vol. 193, s. 175–184. — Bibliogr. s. 183–184, Abstr. — Publikacja dostępna online od: 2017-12-05. — ICMS 2017 : International Conference on Molecular Spectroscopy, 3-7 September 2017, Białka Tatrzańska, Poland
Autor
Słowa kluczowe
Dane bibliometryczne
| ID BaDAP | 111675 |
|---|---|
| Data dodania do BaDAP | 2018-02-08 |
| Tekst źródłowy | URL |
| DOI | 10.1016/j.saa.2017.12.008 |
| Rok publikacji | 2018 |
| Typ publikacji | referat w czasopiśmie |
| Otwarty dostęp |  |
| Czasopismo/seria | Spectrochimica Acta, Part A, Molecular and Biomolecular Spectroscopy |
Abstract
Composites consisting of hydroxyapatite (HA) and chitosan (CTS) have recently been intensively studied. In this work, a novel inorganic-organic (I/O) HA/CTS materials in the form of granules were prepared through a simple solution-based chemical method. During the synthesis of these hybrids, the electrostatic complexes between positively charged, protonated amine groups of chitosan and the negative phosphate species (HPO42 − and H2PO4−) were formed. Our biocomposites belong to the class I of hybrids, which was confirmed by FTIR studies. XRD analysis revealed that the obtained materials consisted of hydroxyapatite as the only crystalline phase. Homogeneous dispersion of the components in HA/CTS composites was confirmed. The use of 17 wt% and 23 wt% of chitosan resulted in approximately 12-fold and 16-fold increase in the compressive strength of HA/CTS as compared to the non-modified HA material. During incubation of the studied materials in SBF, pH of the solution remained close to the physiological one. Formation of apatite layer on their surfaces indicated bioactive nature of the developed biomaterials.
