Szczegóły publikacji
Opis bibliograficzny
Non-contact rapid optical coherence elastography by high-speed 4-D imaging of elastic waves / Shaozhen Song, Soon Joon Yoon, Łukasz AMBROZIŃSKI, Ivan Pelivanov, David Li, Liang Gao, Tueng T. Shen, Matthew O'Donnell, Ruikang K. Wang // W: Optical coherence tomography and coherence domain optical methods in biomedicine XXI : 29 January–1 February 2017, San Francisco, California, Unitetd States / eds. James G. Fujimoto, Joseph A. Izatt, Valery V. Tuchin. — Bellingham : SPIE, cop. 2017. — (Proceedings of SPIE / The International Society for Optical Engineering ; ISSN 0277-786X ; vol. 10053) ; (Progress in Biomedical Optics and Imaging ; ISSN 1605-7422 ; vol. 18 no. 17). — ISBN: 9781510605473; e-ISBN: 9781510605480. — S. 100531Y-1–100531Y-5. — Bibliogr. s. 100531Y-5, Abstr. — Publikacja dostępna online od: 2017-02-17. — Ł. Ambroziński - pierwsza afiliacja: University of Washington, USA
Autorzy (9)
- Song Shaozhen
- Yoon Soon Joon
- AGHAmbroziński Łukasz
- Pelivanov Ivan
- Li David
- Gao Liang
- Shen Tueng T.
- O'Donnell Matthew
- Wang Ruikang K.
Słowa kluczowe
Dane bibliometryczne
| ID BaDAP | 105156 |
|---|---|
| Data dodania do BaDAP | 2017-05-22 |
| DOI | 10.1117/12.2252980 |
| Rok publikacji | 2017 |
| Typ publikacji | materiały konferencyjne (aut.) |
| Otwarty dostęp |  |
| Wydawca | SPIE - The International Society for Optics and Photonics |
| Konferencja | Optical coherence tomography and coherence domain optical methods in biomedicine XXI |
| Czasopisma/serie | Proceedings of SPIE / The International Society for Optical Engineering, Progress in Biomedical Optics and Imaging |
Abstract
Shear wave OCE (SW-OCE) uses an OCT system to track propagating mechanical waves, providing the information needed to map the elasticity of the target sample. In this study we demonstrate high speed, 4D imaging to capture transient mechanical wave propagation. Using a high-speed Fourier domain mode-locked (FDML) swept-source OCT (SS-OCT) system operating at ~1.62 MHz A-line rate, the equivalent volume rate of mechanical wave imaging is 16 kvps (kilo-volumes per second), and total imaging time for a 6 x 6 x 3 mm volume is only 0.32 s. With a displacement sensitivity of ~10 nanometers, the proposed 4D imaging technique provides sufficient temporal and spatial resolution for real-time optical coherence elastography (OCE). Combined with a new air-coupled, high-frequency focused ultrasound stimulator requiring no contact or coupling media, this near real-time system can provide quantitative information on localized viscoelastic properties. SW-OCE measurements are demonstrated on tissue-mimicking phantoms and porcine cornea under various intra-ocular pressures. In addition, elasticity anisotropy in the cornea is observed. Images of the mechanical wave group velocity, which correlates with tissue elasticity, show velocities ranging from 4-20 m/s depending on pressure and propagation direction. These initial results strong suggest that 4D imaging for real-time OCE may enable high-resolution quantitative mapping of tissue biomechanical properties in clinical applications.
