Szczegóły publikacji
Opis bibliograficzny
Acoustic micro-tapping for non-contact 4D imaging of tissue elasticity / Łukasz AMBROZIŃSKI, Shaozhen Song, Soon Joon Yoon, Ivan Pelivanov, David Li, Liang Gao, Tueng T. Shen, Ruikang K. Wang, Matthew O'Donnell // Scientific Reports [Dokument elektroniczny]. — Czasopismo elektroniczne ; ISSN 2045-2322. — 2016 — vol. 6, art. no. 38967, s. 1–11. — Tryb dostępu: http://www.nature.com/articles/srep38967.pdf [2017-01-14]. — Bibliogr. s. 10–11. — Publikacja dostępna online od: 2016-12-23. — Ł. Ambroziński – dod. afiliacja: University of Washington
Autorzy (9)
- AGHAmbroziński Łukasz
- Song Shaozhen
- Yoon Soon Joon
- Pelivanov Ivan
- Li David
- Gao Liang
- Shen Tueng T.
- Wang Ruikang K.
- O'Donnell Matthew
Dane bibliometryczne
| ID BaDAP | 103317 |
|---|---|
| Data dodania do BaDAP | 2017-01-20 |
| DOI | 10.1038/srep38967 |
| Rok publikacji | 2016 |
| Typ publikacji | artykuł w czasopiśmie |
| Otwarty dostęp |  |
| Creative Commons | |
| Czasopismo/seria | Scientific Reports |
Abstract
Elastography plays a key role in characterizing soft media such as biological tissue. Although this technology has found widespread use in both clinical diagnostics and basic science research, nearly all methods require direct physical contact with the object of interest and can even be invasive. For a number of applications, such as diagnostic measurements on the anterior segment of the eye, physical contact is not desired and may even be prohibited. Here we present a fundamentally new approach to dynamic elastography using non-contact mechanical stimulation of soft media with precise spatial and temporal shaping. We call it acoustic micro-tapping (A mu T) because it employs focused, air-coupled ultrasound to induce significant mechanical displacement at the boundary of a soft material using reflection-based radiation force. Combining it with high-speed, four-dimensional (three space dimensions plus time) phase-sensitive optical coherence tomography creates a non-contact tool for high-resolution and quantitative dynamic elastography of soft tissue at near real-time imaging rates. The overall approach is demonstrated in ex-vivo porcine cornea.
