Szczegóły publikacji
Opis bibliograficzny
Hybrid oxide-polymer layer formed on $Ti-15Mo$ alloy surface enhancing antibacterial and osseointegration functions / Alicja Kazek-Kęsik, Joanna Jaworska, Małgorzata KROK-BORKOWICZ, Monika Gołda-Cępa, Małgorzata Pastusiak, Monika Brzychczy-Włoch, Elżbieta PAMUŁA, Andrzej Kotarba, Wojciech Simka // Surface and Coatings Technology ; ISSN 0257-8972. — 2016 — vol. 302, s. 158–165. — Bibliogr. s. 164–165, Abstr. — Publikacja dostępna online od: 2016-05-26
Autorzy (9)
- Kazek-Kęsik Alicja
- Jaworska Joanna
- AGHKrok-Borkowicz Małgorzata
- Gołda-Cępa Monika
- Pastusiak Małgorzata
- Brzychczy-Włoch Monika
- AGHPamuła Elżbieta
- Kotarba Andrzej
- Simka Wojciech
Słowa kluczowe
Dane bibliometryczne
| ID BaDAP | 100468 |
|---|---|
| Data dodania do BaDAP | 2016-10-04 |
| Tekst źródłowy | URL |
| DOI | 10.1016/j.surfcoat.2016.05.073 |
| Rok publikacji | 2016 |
| Typ publikacji | artykuł w czasopiśmie |
| Otwarty dostęp |  |
| Czasopismo/seria | Surface & Coatings Technology |
Abstract
Poly(D,L-lactide-co-glycolide) 50/50 layer was formed on the previously anodized Ti-15Mo alloy surface and evaluated in terms of morphology (SEM), electrochemical analysis and biocompatibility (cell adhesion and biofilm formation tests). The polymer uniformly covered the porous oxide layer and filled the pores. The molar ratio of the comonomers in the copolymer was chosen to obtainthe material, with degradation time of 4 weeks. The degradation process of polymer-oxide coatings was evaluated using H-1 and C-13 NMR. The oxide and polymer-oxide layers were cytocompatible, and osteoblast-like MG-63 cells were well adhered to the modified surfaces. The hybrid gentamicin-PLGA loaded coatings formed on the titanium alloy surface exhibited antimicrobial activity against Staphylococcus aureus. The coatings improved the corrosion resistance of the substrate in Ringer solution. Formation of the hybrid polymer-oxide layer on the Ti-15Mo alloy surface is a promising approach to obtain 'smart materials'. (C) 2016 lsevier B.V. All rights reserved.
