Szczegóły publikacji

Opis bibliograficzny

Blood‑lead level in humans and drug addiction: a comprehensive study in Iran / Amir Ghaderi, Amir Hossein Khoshakhlagh, Agnieszka GRUSZECKA-KOSOWSKA, Fatemeh Alemi, Pooya Hazegh, Zahra Aghaei, Nader Molavi, Mojtaba Mahdavi, Neda Vahed, Somayeh Ghadami Dehkohneh, Fatemeh Ostadmohammady, Darpan Das // Environmental Science and Pollution Research ; ISSN 0944-1344. — 2023 — vol. 30 iss. 52, s. 112071–112085. — Bibliogr. s. 112083–112084, Abstr. — Publikacja dostępna online od: 2023-10-12

Autorzy (12)

  • Ghaderi Amir
  • Khoshakhlagh Amir Hossein
  • AGHGruszecka-Kosowska Agnieszka
  • Alemi Fatemeh
  • Hazegh Pooya
  • Aghaei Zahra
  • Molavi Nader
  • Mahdavi Mojtaba
  • Vahed Neda
  • Dehkohneh Somayeh Ghadami
  • Ostadmohammady Fatemeh
  • Das Darpan

Słowa kluczowe

drug addictionhuman healthblood-lead levelatomic absorption spectrometry

Dane bibliometryczne

ID BaDAP150158
Data dodania do BaDAP2023-11-21
Tekst źródłowyURL
Rok publikacji2023
Typ publikacjiartykuł w czasopiśmie
Otwarty dostęptak
Czasopismo/seriaEnvironmental Science and Pollution Research


Drug abuse has a high prevalence worldwide and causes many health-related disorders. There are limited human exposure studies on establishing lead exposure levels and their propensity for drug addiction. In the present study, blood samples were tested for lead (Pb) concentrations in illicit drug users together with the related symptoms in comparison with control group of non-drug users. The study was performed on 250 volunteers divided equally in four drug groups, namely, opioids, hashish, methadone, and methamphetamine, and one control group of non-drug users. Participants were recruited from drug addiction clinics and camps in Kashan city, Iran, who were using drugs continuously for more than 1 year. Control group was recruited from companions of the patients with no drug use history. In the investigated groups of drug users, the highest blood-lead level (BLL) concentrations were observed in the opioid group (mean 37.57 µg/dL) with almost 3.7 times higher than in the control group (mean 3.39 µg/dL). In the methamphetamine group, type of occupation had the significant association with BLL concentrations. The positive correlation was revealed in the opioid and methadone groups for BLL concentrations and the duration of drug usage. In the opioid group, the highest BLL concentrations were observed among users who used both methods of drug use: smoking and eating. Also, several behavioral and life-style factors were identified which influence the blood-lead concentration in the drug users. The results of our study revealed that the BLL concentrations in investigated drug users’ groups were significantly higher than in the control group (P < 0.001). That can be related with the Pb contents in illicitly used drugs. Apart other adverse health effects, long-term illicit drug use might cause to lead poisoning.

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