Szczegóły publikacji

Opis bibliograficzny

Blood lead concentrations in children with iron deficiency anemia: a systematic review and meta-analysis / Tahere Farkhondeh, Borhan Mansouri, Lukasz J. Binkowski, Martyna Błaszczyk, Meghdad Pirsaheb, Nammam Ali Azadi, Maciej SŁOBODA, Alireza Amirabadizadeh, Seyed Yoosef Javadmoosavi // Environmental Science and Pollution Research ; ISSN 0944-1344. — 2022 — vol. 29 iss. 3, s. 3199–3212. — Bibliogr. s. 3211–3212, Abstr. — Publikacja dostępna online od: 2021-11-03

Autorzy (9)

  • Farkhondeh Tahere
  • Mansouri Borhan
  • Binkowski Lukasz J.
  • Błaszczyk-Altman Martyna
  • Pirsaheb Meghdad
  • Azadi Nammam Ali
  • AGHSłoboda Maciej Marek
  • Amirabadizadeh Alireza
  • Javadmoosavi Seyed Yoosef

Słowa kluczowe

anemiairon deficiencynutritional disorderleadodds ratio

Dane bibliometryczne

ID BaDAP138618
Data dodania do BaDAP2022-01-20
Tekst źródłowyURL
Rok publikacji2022
Typ publikacjiartykuł w czasopiśmie
Otwarty dostęptak
Czasopismo/seriaEnvironmental Science and Pollution Research


Iron deficiency is the most common nutritional disorder detrimental to the behavior, cognitive performance, immune system, and physical growth of infants and preschool- and school-age children. Iron deficiency anemia (IDA) increases children’s susceptibility to some metals, including the highly toxic lead (Pb), but the character of this relationship is still disputed. Thus, this study aimed to review and meta-analyze the association between the IDA and blood lead levels (BLL) among children, based on papers indexed by international scientific databases and published up to September 2021. A search was performed of the literature in several databases including the ISI Web of Science, PubMed, and Scopus. The final papers were assessed concerning their quality based on the Newcastle–Ottawa Scale (NOS) for cross-sectional studies. Moreover, analyses were performed using R statistical software with the “meta” package. Of the 1528 articles found, only 12 studies met the inclusion criteria and were considered in the meta-analysis. Significantly higher BLL in IDA children (SMD = 2.40; CI 95%, 0.93–3.87 µg/L; p = 0.0014) was seen when compared to non-IDA children. Moreover, the pooled OR is equal to 2.75 (CI 95%, 1.10–6.85 µg/L; p = 0.0303) suggesting a higher risk of IDA development among children with BLL > 10 µg/dL. Thus, we recommend systematic monitoring of Fe and Pb levels among children, especially in countries with limited sources of nutritious food. Since only a few studies were available for this meta-analysis, further studies are necessary to examine the association between IDA and BLL in detail.

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